Hi Kuki.....there were three supplements: calcium, ginko bilboa and glucosamine chondroitin. I had been taking them for 8 months before the second wave of allergy season, it may not take that long however. Most Docs say it takes about 1-2 months for them to be in your system to see the progress but again, you have to be sure to take them daily for it to work. Hope it helps, let me know. Seemed like it was more the combination of the 3 that made the difference.